Cholera toxin B induces interleukin-1β production from resident peritoneal macrophages through the pyrin inflammasome as well as the NLRP3 inflammasome

Cholera toxin B (CTB) is a subunit of cholera toxin, a bacterial enterotoxin secreted by Vibrio cholerae and also functions as an immune adjuvant. However, it remains unclear how CTB activates immune cells. We here evaluated whether or how CTB induces production of a pro-inflammatory cytokine, inter...

Descripción completa

Detalles Bibliográficos
Autores principales: Orimo, Takashi, Sasaki, Izumi, Hemmi, Hiroaki, Ozasa, Toshiya, Fukuda-Ohta, Yuri, Ohta, Tomokazu, Morinaka, Mio, Kitauchi, Mariko, Yamaguchi, Takako, Sato, Yayoi, Tanaka, Takashi, Hoshino, Katsuaki, Katayama, Kei-ichi, Fukuda, Shinji, Miyake, Kensuke, Yamamoto, Masahiro, Satoh, Takashi, Furukawa, Koichi, Kuroda, Etsushi, Ishii, Ken J, Takeda, Kiyoshi, Kaisho, Tsuneyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Featured Article of the Month
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749887/
https://www.ncbi.nlm.nih.gov/pubmed/30689886
http://dx.doi.org/10.1093/intimm/dxz004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749887/
https://www.ncbi.nlm.nih.gov/pubmed/30689886
http://dx.doi.org/10.1093/intimm/dxz004

Ejemplares similares