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Spinal microglia contribute to cancer-induced pain through system x(C)(−)-mediated glutamate release

INTRODUCTION: Microglial cells, the resident macrophages of the central nervous system, are a key contributor to the generation and maintenance of cancer-induced pain (CIP). In healthy organisms, activated microglia promote recovery through the release of trophic and anti-inflammatory factors to cle...

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Detalles Bibliográficos
Autores principales: Miladinovic, Tanya, Singh, Gurmit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749914/
https://www.ncbi.nlm.nih.gov/pubmed/31583353
http://dx.doi.org/10.1097/PR9.0000000000000738