Cargando…
Spinal microglia contribute to cancer-induced pain through system x(C)(−)-mediated glutamate release
INTRODUCTION: Microglial cells, the resident macrophages of the central nervous system, are a key contributor to the generation and maintenance of cancer-induced pain (CIP). In healthy organisms, activated microglia promote recovery through the release of trophic and anti-inflammatory factors to cle...
Autores principales: | Miladinovic, Tanya, Singh, Gurmit |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749914/ https://www.ncbi.nlm.nih.gov/pubmed/31583353 http://dx.doi.org/10.1097/PR9.0000000000000738 |
Ejemplares similares
-
Functional effects of TrkA inhibition on system x(C)(−)-mediated glutamate release and cancer-induced bone pain
por: Miladinovic, Tanya, et al.
Publicado: (2018) -
Activation of hippocampal microglia in a murine model of cancer-induced pain
por: Miladinovic, Tanya, et al.
Publicado: (2019) -
Bone cancer-induced pain is associated with glutamate signalling in
peripheral sensory neurons
por: Zhu, Yong Fang, et al.
Publicado: (2020) -
Rat model of cancer-induced bone pain: changes in nonnociceptive sensory neurons in vivo
por: Zhu, Yong Fang, et al.
Publicado: (2017) -
Inflammatory-induced spinal dorsal horn neurons hyperexcitability is mediated by P2X4 receptors
por: Aby, Franck, et al.
Publicado: (2018)