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C57BL/6 and 129 inbred mouse strains differ in Gbp2 and Gbp2b expression in response to inflammatory stimuli in vivo

Background: Infections cause the production of inflammatory cytokines such as Interferon gamma (IFNγ). IFNγ in turn prompts the upregulation of a range of host defence proteins including members of the family of guanylate binding proteins (Gbps). In humans and mice alike, GBPs restrict the intracell...

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Detalles Bibliográficos
Autores principales: Clough, Barbara, Finethy, Ryan, Khan, Rabia T., Fisch, Daniel, Jordan, Sarah, Patel, Harshil, Coers, Jörn, Frickel, Eva-Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749937/
https://www.ncbi.nlm.nih.gov/pubmed/31544161
http://dx.doi.org/10.12688/wellcomeopenres.15329.1