Calpain-10 drives podocyte apoptosis and renal injury in diabetic nephropathy

BACKGROUND: Diabetic nephropathy (DN) is a progressive microvascular complication of diabetes mellitus (DM), driven largely by podocyte apoptosis. The cysteine protease Calpain 10 is known to augment apoptosis and necrosis, and is a potential therapeutic target in DN. METHODS: Type 2 diabetes was in...

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Detalles Bibliográficos
Autores principales: Wang, Tao, Gao, Yanbin, Wang, Xiaolei, Shi, Yimin, Xu, Jiayi, Wu, Bingjie, He, Jiaxin, Li, Yimeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750010/
https://www.ncbi.nlm.nih.gov/pubmed/31571956
http://dx.doi.org/10.2147/DMSO.S217924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750010/
https://www.ncbi.nlm.nih.gov/pubmed/31571956
http://dx.doi.org/10.2147/DMSO.S217924

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