Hypertensive APOL1 risk allele carriers demonstrate greater blood pressure reduction with angiotensin receptor blockade compared to low risk carriers

BACKGROUND: Hypertension (HTN) disproportionately affects African Americans (AAs), who respond better to thiazide diuretics than other antihypertensives. Variants of the APOL1 gene found in AAs are associated with a higher rate of kidney disease and play a complex role in cardiovascular disease. MET...

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Detalles Bibliográficos
Autores principales: Cunningham, Patrick N., Wang, Zhiying, Grove, Megan L., Cooper-DeHoff, Rhonda M., Beitelshees, Amber L., Gong, Yan, Gums, John G., Johnson, Julie A., Turner, Stephen T., Boerwinkle, Eric, Chapman, Arlene B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750571/
https://www.ncbi.nlm.nih.gov/pubmed/31532792
http://dx.doi.org/10.1371/journal.pone.0221957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750571/
https://www.ncbi.nlm.nih.gov/pubmed/31532792
http://dx.doi.org/10.1371/journal.pone.0221957

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