Cargando…

EGF receptor stimulation shifts breast cancer cell glucose metabolism toward glycolytic flux through PI3 kinase signaling

Breast cancers that express epidermal growth factor (EGF) receptors (EGFRs) are associated with poor prognosis. Our group recently showed in breast cancer patients that EGFR expression is strongly correlated with high tumor uptake of the glucose analogue, (18)F-fluorodeoxyglucose (FDG). Here, we exp...

Descripción completa

Detalles Bibliográficos
Autores principales: Jung, Kyung-Ho, Lee, Eun Jeong, Park, Jin Won, Lee, Jin Hee, Moon, Seung Hwan, Cho, Young Seok, Lee, Kyung-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750601/
https://www.ncbi.nlm.nih.gov/pubmed/31532771
http://dx.doi.org/10.1371/journal.pone.0221294