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EGF receptor stimulation shifts breast cancer cell glucose metabolism toward glycolytic flux through PI3 kinase signaling
Breast cancers that express epidermal growth factor (EGF) receptors (EGFRs) are associated with poor prognosis. Our group recently showed in breast cancer patients that EGFR expression is strongly correlated with high tumor uptake of the glucose analogue, (18)F-fluorodeoxyglucose (FDG). Here, we exp...
Autores principales: | Jung, Kyung-Ho, Lee, Eun Jeong, Park, Jin Won, Lee, Jin Hee, Moon, Seung Hwan, Cho, Young Seok, Lee, Kyung-Han |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750601/ https://www.ncbi.nlm.nih.gov/pubmed/31532771 http://dx.doi.org/10.1371/journal.pone.0221294 |
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