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PLK1 contributes to autophagy by regulating MYC stabilization in osteosarcoma cells

BACKGROUND: PLK1, a typical PLK protein, is the main driver of cancer cell growth and proliferation. It is an inhibitor of the protein kinases that is currently being investigated in clinical studies. It is often used as a tumor marker, as high PLK1 expression correlates with poor prognosis in cance...

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Detalles Bibliográficos
Autores principales: Mo, Hao, He, Juliang, Yuan, Zhenchao, Wu, Zhenjie, Liu, Bin, Lin, Xiang, Guan, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750617/
https://www.ncbi.nlm.nih.gov/pubmed/31571905
http://dx.doi.org/10.2147/OTT.S210575