Non-catalytic Roles of Tet2 Are Essential to Regulate Hematopoietic Stem and Progenitor Cell Homeostasis

The Ten-eleven translocation (TET) enzymes regulate gene expression by promoting DNA demethylation and partnering with chromatin modifiers. TET2, a member of this family, is frequently mutated in hematological disorders. The contributions of TET2 in hematopoiesis have been attributed to its DNA deme...

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Detalles Bibliográficos
Autores principales: Ito, Kyoko, Lee, Joun, Chrysanthou, Stephanie, Zhao, Yilin, Josephs, Katherine, Sato, Hiroyo, Teruya-Feldstein, Julie, Zheng, Deyou, Dawlaty, Meelad M., Ito, Keisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750732/
https://www.ncbi.nlm.nih.gov/pubmed/31484061
http://dx.doi.org/10.1016/j.celrep.2019.07.094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750732/
https://www.ncbi.nlm.nih.gov/pubmed/31484061
http://dx.doi.org/10.1016/j.celrep.2019.07.094

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