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Functionalization of Liposomes with Hydrophilic Polymers Results in Macrophage Uptake Independent of the Protein Corona

[Image: see text] Liposomes are established drug carriers that are employed to transport and deliver hydrophilic drugs in the body. To minimize unspecific cellular uptake, nanocarriers are commonly modified with poly(ethylene glycol) (PEG), which is known to minimize unspecific protein adsorption. H...

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Detalles Bibliográficos
Autores principales: Weber, Claudia, Voigt, Matthias, Simon, Johanna, Danner, Ann-Kathrin, Frey, Holger, Mailänder, Volker, Helm, Mark, Morsbach, Svenja, Landfester, Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750830/
https://www.ncbi.nlm.nih.gov/pubmed/31268685
http://dx.doi.org/10.1021/acs.biomac.9b00539