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trans-Diastereoselective Ru(II)-Catalyzed Asymmetric Transfer Hydrogenation of α-Acetamido Benzocyclic Ketones via Dynamic Kinetic Resolution

[Image: see text] A highly efficient enantio- and diastereoselective catalyzed asymmetric transfer hydrogenation via dynamic kinetic resolution (DKR–ATH) of α,β-dehydro-α-acetamido and α-acetamido benzocyclic ketones to ent-trans-β-amido alcohols is disclosed employing a new ansa-Ru(II) complex of a...

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Detalles Bibliográficos
Autores principales: Cotman, Andrej Emanuel, Lozinšek, Matic, Wang, Baifan, Stephan, Michel, Mohar, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750876/
https://www.ncbi.nlm.nih.gov/pubmed/31058516
http://dx.doi.org/10.1021/acs.orglett.9b01069