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Effect of glutaminase inhibition on cancer-induced bone pain
PURPOSE: The complex nature of cancer-induced bone pain (CIBP) has led to investigation into cancer-targeted therapies. This has involved targeting glutamate release from the tumor, secreted as a byproduct of antioxidant responses and metabolic disruption. Cancer cells undergo many metabolic changes...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750878/ https://www.ncbi.nlm.nih.gov/pubmed/31571981 http://dx.doi.org/10.2147/BCTT.S215655 |