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Lens Connexin Channels Have Differential Permeability to the Second Messenger cAMP

PURPOSE: Gap junction channels exhibit connexin specific biophysical properties, including the selective intercellular passage of larger solutes, such as second messengers. Here, we have examined the cyclic nucleotide permeability of the lens connexins, which could influence events like epithelial c...

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Detalles Bibliográficos
Autores principales: Valiunas, Virginijus, Brink, Peter R., White, Thomas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750889/
https://www.ncbi.nlm.nih.gov/pubmed/31529078
http://dx.doi.org/10.1167/iovs.19-27302