Molecular function limits divergent protein evolution on planetary timescales

Functional conservation is known to constrain protein evolution. Nevertheless, the long-term divergence patterns of proteins maintaining the same molecular function and the possible limits of this divergence have not been explored in detail. We investigate these fundamental questions by characterizi...

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Detalles Bibliográficos
Autores principales: Konaté, Mariam M, Plata, Germán, Park, Jimin, Usmanova, Dinara R, Wang, Harris, Vitkup, Dennis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Evolutionary Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750897/
https://www.ncbi.nlm.nih.gov/pubmed/31532392
http://dx.doi.org/10.7554/eLife.39705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750897/
https://www.ncbi.nlm.nih.gov/pubmed/31532392
http://dx.doi.org/10.7554/eLife.39705

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