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Large-scale RNAi screen identified Dhpr as a regulator of mitochondrial morphology and tissue homeostasis
Mitochondria are highly dynamic organelles. Through a large-scale in vivo RNA interference (RNAi) screen that covered around a quarter of the Drosophila melanogaster genes (4000 genes), we identified 578 genes whose knockdown led to aberrant shapes or distributions of mitochondria. The complex analy...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750926/ https://www.ncbi.nlm.nih.gov/pubmed/31555733 http://dx.doi.org/10.1126/sciadv.aax0365 |