Release of cholesterol-rich particles from the macrophage plasma membrane during movement of filopodia and lamellipodia

Cultured mouse peritoneal macrophages release large numbers of ~30-nm cholesterol-rich particles. Here, we show that those particles represent fragments of the plasma membrane that are pulled away and left behind during the projection and retraction of filopodia and lamellipodia. Consistent with thi...

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Detalles Bibliográficos
Autores principales: Hu, Xuchen, Weston, Thomas A, He, Cuiwen, Jung, Rachel S, Heizer, Patrick J, Young, Brian D, Tu, Yiping, Tontonoz, Peter, Wohlschlegel, James A, Jiang, Haibo, Young, Stephen G, Fong, Loren G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750930/
https://www.ncbi.nlm.nih.gov/pubmed/31486771
http://dx.doi.org/10.7554/eLife.50231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750930/
https://www.ncbi.nlm.nih.gov/pubmed/31486771
http://dx.doi.org/10.7554/eLife.50231

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