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Lrg1 Regulates β (1,3)-Glucan Masking in Candida albicans through the Cek1 MAP Kinase Pathway

Candida albicans is among the most prevalent opportunistic human fungal pathogens. The ability to mask the immunogenic polysaccharide β (1,3)-glucan from immune detection via a layer of mannosylated proteins is a key virulence factor of C. albicans. We previously reported that hyperactivation of the...

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Detalles Bibliográficos
Autores principales: Chen, Tian, Wagner, Andrew S., Tams, Robert N., Eyer, James E., Kauffman, Sarah J., Gann, Eric R., Fernandez, Elias J., Reynolds, Todd B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751057/
https://www.ncbi.nlm.nih.gov/pubmed/31530671
http://dx.doi.org/10.1128/mBio.01767-19