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Exosomes derived from cardiac progenitor cells attenuate CVB3-induced apoptosis via abrogating the proliferation of CVB3 and modulating the mTOR signaling pathways

Viral myocarditis is potentially fatal and lacking a specific treatment. Exosomes secreted by cardiac progenitor cells (CPCs) have emerged as a promising tool for cardioprotection and repair. In this study, we investigated whether CPCs-derived exosomes (CPCs-Ex) could utilize the mTOR signal pathway...

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Detalles Bibliográficos
Autores principales: Li, Xin, Yang, Zuocheng, Nie, Wenyuan, Jiang, Jie, Li, Shentang, Li, Zhuoying, Tian, Lang, Ma, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751166/
https://www.ncbi.nlm.nih.gov/pubmed/31534118
http://dx.doi.org/10.1038/s41419-019-1910-9