Cargando…
Exosomes derived from cardiac progenitor cells attenuate CVB3-induced apoptosis via abrogating the proliferation of CVB3 and modulating the mTOR signaling pathways
Viral myocarditis is potentially fatal and lacking a specific treatment. Exosomes secreted by cardiac progenitor cells (CPCs) have emerged as a promising tool for cardioprotection and repair. In this study, we investigated whether CPCs-derived exosomes (CPCs-Ex) could utilize the mTOR signal pathway...
Autores principales: | Li, Xin, Yang, Zuocheng, Nie, Wenyuan, Jiang, Jie, Li, Shentang, Li, Zhuoying, Tian, Lang, Ma, Xing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751166/ https://www.ncbi.nlm.nih.gov/pubmed/31534118 http://dx.doi.org/10.1038/s41419-019-1910-9 |
Ejemplares similares
-
The PI3K/Akt/mTOR pathway is involved in CVB3-induced autophagy of HeLa cells
por: Chang, Huan, et al.
Publicado: (2017) -
Cardiac progenitor cell-derived exosomes promote H9C2 cell growth via Akt/mTOR activation
por: Li, Shentang, et al.
Publicado: (2018) -
CVB3 VP1 interacts with MAT1 to inhibit cell proliferation by interfering with Cdk-activating kinase complex activity in CVB3-induced acute pancreatitis
por: Zhang, Hongxia, et al.
Publicado: (2021) -
TFRC upregulation promotes ferroptosis in CVB3 infection via nucleus recruitment of Sp1
por: Yi, Lu, et al.
Publicado: (2022) -
CVB3-Mediated Mitophagy Plays an Important Role in Viral Replication via Abrogation of Interferon Pathways
por: Oh, Soo-Jin, et al.
Publicado: (2021)