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Modular enzyme assembly for enhanced cascade biocatalysis and metabolic flux

Enzymatic reactions in living cells are highly dynamic but simultaneously tightly regulated. Enzyme engineers seek to construct multienzyme complexes to prevent intermediate diffusion, to improve product yield, and to control the flux of metabolites. Here we choose a pair of short peptide tags (RIAD...

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Detalles Bibliográficos
Autores principales: Kang, Wei, Ma, Tian, Liu, Min, Qu, Jiale, Liu, Zhenjun, Zhang, Huawei, Shi, Bin, Fu, Shuai, Ma, Juncai, Lai, Louis Tung Faat, He, Sicong, Qu, Jianan, Wing-Ngor Au, Shannon, Ho Kang, Byung, Yu Lau, Wilson Chun, Deng, Zixin, Xia, Jiang, Liu, Tiangang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751169/
https://www.ncbi.nlm.nih.gov/pubmed/31534134
http://dx.doi.org/10.1038/s41467-019-12247-w