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Rapid Detection of Genetic Engineering, Structural Variation, and Antimicrobial Resistance Markers in Bacterial Biothreat Pathogens by Nanopore Sequencing

Widespread release of Bacillus anthracis (anthrax) or Yersinia pestis (plague) would prompt a public health emergency. During an exposure event, high-quality whole genome sequencing (WGS) can identify genetic engineering, including the introduction of antimicrobial resistance (AMR) genes. Here, we d...

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Detalles Bibliográficos
Autores principales: Gargis, Amy S., Cherney, Blake, Conley, Andrew B., McLaughlin, Heather P., Sue, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751186/
https://www.ncbi.nlm.nih.gov/pubmed/31534162
http://dx.doi.org/10.1038/s41598-019-49700-1