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Lung endothelial cell antigen cross-presentation to CD8(+)T cells drives malaria-associated lung injury

Malaria-associated acute respiratory distress syndrome (ARDS) and acute lung injury (ALI) are life-threatening manifestations of severe malaria infections. The pathogenic mechanisms that lead to respiratory complications, such as vascular leakage, remain unclear. Here, we confirm that depleting CD8(...

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Detalles Bibliográficos
Autores principales: Claser, Carla, Nguee, Samantha Yee Teng, Balachander, Akhila, Wu Howland, Shanshan, Becht, Etienne, Gunasegaran, Bavani, Hartimath, Siddesh V., Lee, Audrey W. Q., Theng Theng Ho, Jacqueline, Bing Ong, Chee, Newell, Evan W., Goggi, Julian, Guan Ng, Lai, Renia, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751193/
https://www.ncbi.nlm.nih.gov/pubmed/31534124
http://dx.doi.org/10.1038/s41467-019-12017-8