Cargando…

RNA-binding protein CELF6 is cell cycle regulated and controls cancer cell proliferation by stabilizing p21

CELF6, a member of the CELF family of RNA-binding proteins, regulates muscle-specific alternative splicing and contributes to the pathogenesis of myotonic dystrophy (DM), however the role of CELF6 in cancer cell proliferation is less appreciated. Here, we show that the expression of CELF6 is cell cy...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Gang, Zhang, Qianwen, Xia, Li, Shi, Mengjuan, Cai, Jin, Zhang, Haowei, Li, Jia, Lin, Guanglan, Xie, Weidong, Zhang, Yaou, Xu, Naihan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751195/
https://www.ncbi.nlm.nih.gov/pubmed/31534127
http://dx.doi.org/10.1038/s41419-019-1927-0