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An aggregon in conductin/axin2 regulates Wnt/β-catenin signaling and holds potential for cancer therapy

The paralogous scaffold proteins axin and conductin/axin2 are key factors in the negative regulation of the Wnt pathway transcription factor β-catenin, thereby representing interesting targets for signaling regulation. Polymerization of axin proteins is essential for their activity in suppressing Wn...

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Detalles Bibliográficos
Autores principales:	Bernkopf, Dominic B., Brückner, Martina, Hadjihannas, Michel V., Behrens, Jürgen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751202/ https://www.ncbi.nlm.nih.gov/pubmed/31534175 http://dx.doi.org/10.1038/s41467-019-12203-8

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