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Dynasore suppresses cell proliferation, migration, and invasion and enhances the antitumor capacity of cisplatin via STAT3 pathway in osteosarcoma

Osteosarcoma (OS) is the most common malignant bone tumor. The prognosis of metastatic and recurrent OS patients still remains unsatisfactory. Cisplatin reveals undeniable anti-tumor effect while induces severe side effects that threatening patients’ health. Dynasore, a cell-permeable small molecule...

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Detalles Bibliográficos
Autores principales: Zhong, Binlong, Shi, Deyao, Wu, Fashuai, Wang, Shangyu, Hu, Hongzhi, Cheng, Cheng, Qing, Xiangcheng, Huang, Xin, Luo, Xueying, Zhang, Zhicai, Shao, Zengwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751204/
https://www.ncbi.nlm.nih.gov/pubmed/31534119
http://dx.doi.org/10.1038/s41419-019-1917-2