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The mechanism of the premetastatic niche facilitating colorectal cancer liver metastasis generated from myeloid-derived suppressor cells induced by the S1PR1–STAT3 signaling pathway

The tumor-derived factors involved in the expansion and accumulation of myeloid-derived suppressor cells (MDSCs) in metastatic dissemination of colorectal cancer (CRC) to the liver has not been studied. Immunohistochemistry was used to detect sphingosine-1-phosphate receptor 1 (S1PR1) and signal tra...

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Detalles Bibliográficos
Autores principales: Lin, Qi, Ren, Li, Jian, Mi, Xu, Pingping, Li, Jun, Zheng, Peng, Feng, Qingyang, Yang, Liangliang, Ji, Meilin, Wei, Ye, Xu, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751205/
https://www.ncbi.nlm.nih.gov/pubmed/31534132
http://dx.doi.org/10.1038/s41419-019-1922-5