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Toll-Like Receptor 7 Activation Enhances CD8+ T Cell Effector Functions by Promoting Cellular Glycolysis

The activation of TLR7 signaling in T cells accelerates antigen-specific responses. Such responses play an essential role in eliminating viral infections and can be anti-tumorigenic. However, the underlying mechanisms of how TLR7 can promote the optimal function of CD8+ T cells remain unclear. To in...

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Detalles Bibliográficos
Autores principales: Li, Qian, Yan, Yan, Liu, Jia, Huang, Xuan, Zhang, Xiaoyong, Kirschning, Carsten, Xu, Haifeng C., Lang, Philipp A., Dittmer, Ulf, Zhang, Ejuan, Lu, Mengji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751247/
https://www.ncbi.nlm.nih.gov/pubmed/31572396
http://dx.doi.org/10.3389/fimmu.2019.02191