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Systemic and Intra-Nodal Activation of NK Cells After Rituximab Monotherapy for Follicular Lymphoma

Monotherapy with the anti-CD20 monoclonal antibody rituximab can induce complete responses (CR) in patients with follicular lymphoma (FL). Resting FcRγIII(+) (CD16(+)) natural killer (NK) cells respond strongly to rituximab-coated target cells in vitro. Yet, the contribution of NK cells in the thera...

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Detalles Bibliográficos
Autores principales: Enqvist, Monika, Jacobs, Benedikt, Junlén, Henna R., Schaffer, Marie, Melén, Christopher M., Friberg, Danielle, Wahlin, Björn Engelbrekt, Malmberg, Karl-Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751265/
https://www.ncbi.nlm.nih.gov/pubmed/31572357
http://dx.doi.org/10.3389/fimmu.2019.02085