Increased miR-142-3p Expression Might Explain Reduced Regulatory T Cell Function in Granulomatosis With Polyangiitis

Objectives: Regulatory T cells (Tregs) are frequently functionally impaired in patients with granulomatosis with polyangiitis (GPA). However, the mechanism underlying their impaired function is unknown. Here, we hypothesized that Treg dysfunction in GPA is due to altered microRNA (miRNA) expression....

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Detalles Bibliográficos
Autores principales: Dekkema, Gerjan J., Bijma, Theo, Jellema, Pytrick G., Van Den Berg, Anke, Kroesen, Bart-Jan, Stegeman, Coen A., Heeringa, Peter, Abdulahad, Wayel H., Sanders, Jan-Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751284/
https://www.ncbi.nlm.nih.gov/pubmed/31572380
http://dx.doi.org/10.3389/fimmu.2019.02170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751284/
https://www.ncbi.nlm.nih.gov/pubmed/31572380
http://dx.doi.org/10.3389/fimmu.2019.02170

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