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Molecular Adjuvants Based on Plasmids Encoding Protein Aggregation Domains Affect Bone Marrow Niche Homeostasis

BACKGROUND: During last years, DNA vaccine immunogenicity has been optimized by the employment of co-stimulatory molecules and molecular adjuvants. It has been reported that plasmid (pATRex), encompassing the DNA sequence for the von Willebrand A (vWA/A) domain of the An-thrax Toxin Receptor-1 (ANTX...

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Detalles Bibliográficos
Autores principales: Sabbieti, Maria Giovanna, Lacava, Giovanna, Amaroli, Andrea, Marchetti, Luigi, Censi, Roberta, Di Martino, Piera, Agas, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751345/
https://www.ncbi.nlm.nih.gov/pubmed/29303078
http://dx.doi.org/10.2174/1566523218666180105122626