Mechanistic insights into the protective roles of polyphosphate against amyloid cytotoxicity

The universally abundant polyphosphate (polyP) accelerates fibril formation of disease-related amyloids and protects against amyloid cytotoxicity. To gain insights into the mechanism(s) by which polyP exerts these effects, we focused on α-synuclein, a well-studied amyloid protein, which constitutes...

Descripción completa

Detalles Bibliográficos
Autores principales: Lempart, Justine, Tse, Eric, Lauer, James A, Ivanova, Magdalena I, Sutter, Alexandra, Yoo, Nicholas, Huettemann, Philipp, Southworth, Daniel, Jakob, Ursula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751573/
https://www.ncbi.nlm.nih.gov/pubmed/31533964
http://dx.doi.org/10.26508/lsa.201900486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751573/
https://www.ncbi.nlm.nih.gov/pubmed/31533964
http://dx.doi.org/10.26508/lsa.201900486

Ejemplares similares