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Mechanistic insights into the protective roles of polyphosphate against amyloid cytotoxicity

The universally abundant polyphosphate (polyP) accelerates fibril formation of disease-related amyloids and protects against amyloid cytotoxicity. To gain insights into the mechanism(s) by which polyP exerts these effects, we focused on α-synuclein, a well-studied amyloid protein, which constitutes...

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Detalles Bibliográficos
Autores principales:	Lempart, Justine, Tse, Eric, Lauer, James A, Ivanova, Magdalena I, Sutter, Alexandra, Yoo, Nicholas, Huettemann, Philipp, Southworth, Daniel, Jakob, Ursula
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Life Science Alliance LLC 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751573/ https://www.ncbi.nlm.nih.gov/pubmed/31533964 http://dx.doi.org/10.26508/lsa.201900486

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