A Bayesian non-inferiority approach using experts’ margin elicitation – application to the monitoring of safety events

BACKGROUND: When conducing Phase-III trial, regulatory agencies and investigators might want to get reliable information about rare but serious safety outcomes during the trial. Bayesian non-inferiority approaches have been developed, but commonly utilize historical placebo-controlled data to define...

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Detalles Bibliográficos
Autores principales: Aupiais, Camille, Alberti, Corinne, Schmitz, Thomas, Baud, Olivier, Ursino, Moreno, Zohar, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751616/
https://www.ncbi.nlm.nih.gov/pubmed/31533631
http://dx.doi.org/10.1186/s12874-019-0826-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751616/
https://www.ncbi.nlm.nih.gov/pubmed/31533631
http://dx.doi.org/10.1186/s12874-019-0826-5

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