Assessing effectiveness of aripiprazole lauroxil vs placebo for the treatment of schizophrenia using number needed to treat and number needed to harm

OBJECTIVE: Schizophrenia clinical trials commonly measure observed changes in Positive and Negative Syndrome Scale (PANSS) total score. However, it is more intuitive to think of response vs nonresponse, a binary outcome. Assessing binary outcomes enables calculation of number needed to treat (NNT) f...

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Detalles Bibliográficos
Autores principales: Citrome, Leslie, Du, Yangchun, Weiden, Peter J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751763/
https://www.ncbi.nlm.nih.gov/pubmed/31686823
http://dx.doi.org/10.2147/NDT.S207910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751763/
https://www.ncbi.nlm.nih.gov/pubmed/31686823
http://dx.doi.org/10.2147/NDT.S207910

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