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Systematic review of basket trials, umbrella trials, and platform trials: a landscape analysis of master protocols
BACKGROUND: Master protocols, classified as basket trials, umbrella trials, and platform trials, are novel designs that investigate multiple hypotheses through concurrent sub-studies (e.g., multiple treatments or populations or that allow adding/removing arms during the trial), offering enhanced eff...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751792/ https://www.ncbi.nlm.nih.gov/pubmed/31533793 http://dx.doi.org/10.1186/s13063-019-3664-1 |