Cargando…

Systematic review of basket trials, umbrella trials, and platform trials: a landscape analysis of master protocols

BACKGROUND: Master protocols, classified as basket trials, umbrella trials, and platform trials, are novel designs that investigate multiple hypotheses through concurrent sub-studies (e.g., multiple treatments or populations or that allow adding/removing arms during the trial), offering enhanced eff...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Jay J. H, Siden, Ellie, Zoratti, Michael J., Dron, Louis, Harari, Ofir, Singer, Joel, Lester, Richard T., Thorlund, Kristian, Mills, Edward J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751792/
https://www.ncbi.nlm.nih.gov/pubmed/31533793
http://dx.doi.org/10.1186/s13063-019-3664-1