Closed system RT-qPCR as a potential companion diagnostic test for immunotherapy outcome in metastatic melanoma

BACKGROUND: In melanoma, there is no companion diagnostic test to predict response to programmed cell death 1 (PD-1) axis immune checkpoint inhibitor (ICI) therapy. In the adjuvant setting, only one in five patients may benefit from ICI, so a biomarker is needed to select those that may or may not b...

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Detalles Bibliográficos
Autores principales: Gupta, Swati, McCann, Leena, Chan, Yvonne G. Y., Lai, Edwin W., Wei, Wei, Wong, Pok Fai, Smithy, James W., Weidler, Jodi, Rhees, Brian, Bates, Michael, Kluger, Harriet M., Rimm, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751819/
https://www.ncbi.nlm.nih.gov/pubmed/31533832
http://dx.doi.org/10.1186/s40425-019-0731-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751819/
https://www.ncbi.nlm.nih.gov/pubmed/31533832
http://dx.doi.org/10.1186/s40425-019-0731-9

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