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Long non-coding RNA HOTTIP enhances IL-6 expression to potentiate immune escape of ovarian cancer cells by upregulating the expression of PD-L1 in neutrophils

BACKGROUND: Long non-coding RNA (lncRNA) HOXA transcript at the distal tip (HOTTIP), has been demonstrated to be a vital biomarker when evaluating the prognosis of multiple cancers. Nevertheless, the potential function of HOTTIP in ovarian cancer (OC), a prevalent cancer among women worldwide, remai...

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Detalles Bibliográficos
Autores principales: Shang, Anquan, Wang, Weiwei, Gu, Chenzheng, Chen, Chen, Zeng, Bingjie, Yang, Yibao, Ji, Ping, Sun, Junjun, Wu, Junlu, Lu, Wenying, Sun, Zujun, Li, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751824/
https://www.ncbi.nlm.nih.gov/pubmed/31533774
http://dx.doi.org/10.1186/s13046-019-1394-6