Downregulation of SIRT2 by Chronic Stress Reduces Expression of Synaptic Plasticity-related Genes through the Upregulation of Ehmt2

Silent information regulator 2 (Sirtuin2 / SIRT2) is a NAD(+)-dependent deacetylase that regulates the cellular oxidative stress response. It modulates transcriptional silencing and protein stability through deacetylation of target proteins including histones. Previous studies have shown that SIRT2...

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Detalles Bibliográficos
Autores principales: Wang, Sung Eun, Ko, Seung Yeon, Jo, Sungsin, Jo, Hye-Ryeong, Han, Jinil, Kim, Yong-Seok, Son, Hyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Sciences 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751865/
https://www.ncbi.nlm.nih.gov/pubmed/31495082
http://dx.doi.org/10.5607/en.2019.28.4.537

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751865/
https://www.ncbi.nlm.nih.gov/pubmed/31495082
http://dx.doi.org/10.5607/en.2019.28.4.537

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