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Downregulation of SIRT2 by Chronic Stress Reduces Expression of Synaptic Plasticity-related Genes through the Upregulation of Ehmt2
Silent information regulator 2 (Sirtuin2 / SIRT2) is a NAD(+)-dependent deacetylase that regulates the cellular oxidative stress response. It modulates transcriptional silencing and protein stability through deacetylation of target proteins including histones. Previous studies have shown that SIRT2...
Autores principales: | Wang, Sung Eun, Ko, Seung Yeon, Jo, Sungsin, Jo, Hye-Ryeong, Han, Jinil, Kim, Yong-Seok, Son, Hyeon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society for Brain and Neural Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751865/ https://www.ncbi.nlm.nih.gov/pubmed/31495082 http://dx.doi.org/10.5607/en.2019.28.4.537 |
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