Angiopoietin-Like Protein 4 (ANGPTL4) Induces Retinal Pigment Epithelial Barrier Breakdown by Activating Signal Transducer and Activator of Transcription 3 (STAT3): Evidence from ARPE-19 Cells Under Hypoxic Condition and Diabetic Rats

BACKGROUND: Diabetic retinopathy is a primary contributor of visual impairment in adult diabetes mellitus patients. Diabetic retinopathy causes breakdown of blood retinal barrier (BRB), and leads to diabetic macular edema. Previous studies have demonstrated angiopoietin-like protein 4 (ANGPTL4) as a...

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Detalles Bibliográficos
Autores principales: Yang, Xinyue, Cao, Jinfeng, Du, Yang, Gong, Qiaoyun, Cheng, Yan, Su, Guanfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Animal Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752095/
https://www.ncbi.nlm.nih.gov/pubmed/31494661
http://dx.doi.org/10.12659/MSM.915748

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752095/
https://www.ncbi.nlm.nih.gov/pubmed/31494661
http://dx.doi.org/10.12659/MSM.915748

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