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Evaluation of immune protection against Toxoplasma gondii infection in mice induced by a multi-antigenic DNA vaccine containing TgGRA24, TgGRA25 and TgMIC6

Toxoplasma gondii infection is prevalent in humans and animals worldwide. In this study, recombinant eukaryotic expression plasmids (pVAX-GRA24, pVAX-GRA25 and pVAX-MIC6) were constructed, and then injected into Kunming mice intramuscularly, as cocktailed plasmids or as single-gene plasmids. We eval...

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Detalles Bibliográficos
Autores principales: Xu, Xiao-Pei, Liu, Wen-Ge, Xu, Qian-Ming, Zhu, Xing-Quan, Chen, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: EDP Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752116/
https://www.ncbi.nlm.nih.gov/pubmed/31535970
http://dx.doi.org/10.1051/parasite/2019050