Zein-alpha lipoic acid-loaded nanoparticles to enhance the oral bioavailability of dapoxetine: optimization and clinical pharmacokinetic evaluation

BACKGROUND: Premature ejaculation (PE) is the most common type of male sexual disorder with important psychological consequences. Dapoxetine (DPX), a recently approved drug for the treatment of PE, suffers from low bioavailability with large variability that ranges from 15–76% (mean 42%) after oral...

Descripción completa

Detalles Bibliográficos
Autores principales: El-Say, Khalid M, Ahmed, Osama AA, Mohamed, Amir I, Safo, Martin K, Omar, Abdelsattar M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752166/
https://www.ncbi.nlm.nih.gov/pubmed/31686817
http://dx.doi.org/10.2147/IJN.S224611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752166/
https://www.ncbi.nlm.nih.gov/pubmed/31686817
http://dx.doi.org/10.2147/IJN.S224611

Ejemplares similares