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Zein-alpha lipoic acid-loaded nanoparticles to enhance the oral bioavailability of dapoxetine: optimization and clinical pharmacokinetic evaluation

BACKGROUND: Premature ejaculation (PE) is the most common type of male sexual disorder with important psychological consequences. Dapoxetine (DPX), a recently approved drug for the treatment of PE, suffers from low bioavailability with large variability that ranges from 15–76% (mean 42%) after oral...

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Detalles Bibliográficos
Autores principales:	El-Say, Khalid M, Ahmed, Osama AA, Mohamed, Amir I, Safo, Martin K, Omar, Abdelsattar M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752166/ https://www.ncbi.nlm.nih.gov/pubmed/31686817 http://dx.doi.org/10.2147/IJN.S224611

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