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R2* Relaxation Affects Pharmacokinetic Analysis of Dynamic Contrast-Enhanced MRI in Cancer and Underestimates Treatment Response at 7 T

Effective transverse relaxivity of gadolinium-based contrast agents is often neglected in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). Here, we assess time and tissue dependence of R2* enhancement and its impact on pharmacokinetic parameter quantification and treatment monitoring....

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Detalles Bibliográficos
Autores principales: Kim, Jana, Moestue, Siver A., Bathen, Tone F., Kim, Eugene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Grapho Publications, LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752293/
https://www.ncbi.nlm.nih.gov/pubmed/31572792
http://dx.doi.org/10.18383/j.tom.2019.00015