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Human cord blood (hCB)-CD34(+) humanized mice fail to reject human acute myeloid leukemia cells

Since their appearance, humanized mice carrying human immune system seemed promising tools to study the crosstalk between cancer and immunity. The NOD-scidIL2Rgamma(null) (NSG) mice engrafted with human cord blood (hCB)-CD34(+) cells have been proposed to be a valuable tool to reproduce human immune...

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Detalles Bibliográficos
Autores principales: Tanaskovic, Olga, Verga Falzacappa, Maria Vittoria, Pelicci, Pier Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752751/
https://www.ncbi.nlm.nih.gov/pubmed/31536492
http://dx.doi.org/10.1371/journal.pone.0217345