The effect of memantine, an antagonist of the NMDA glutamate receptor, in in vitro and in vivo infections by Trypanosoma cruzi

Chagas disease, caused by Trypanosoma cruzi, is a neglected tropical disease that affects 5–6 million people in endemic areas of the Americas. Presently, chemotherapy relies on two compounds that were proposed as trypanocidal drugs four decades ago: nifurtimox and benznidazole. Both drugs are able t...

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Detalles Bibliográficos
Autores principales: Santos Souza, Higo Fernando, Rocha, Sandra Carla, Damasceno, Flávia Silva, Rapado, Ludmila Nakamura, Pral, Elisabeth Mieko Furusho, Marinho, Claudio Romero Farias, Silber, Ariel Mariano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752752/
https://www.ncbi.nlm.nih.gov/pubmed/31536489
http://dx.doi.org/10.1371/journal.pntd.0007226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752752/
https://www.ncbi.nlm.nih.gov/pubmed/31536489
http://dx.doi.org/10.1371/journal.pntd.0007226

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