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Molecular basis of dengue virus serotype 2 morphological switch from 29°C to 37°C
The ability of DENV2 to display different morphologies (hence different antigenic properties) complicates vaccine and therapeutics development. Previous studies showed most strains of laboratory adapted DENV2 particles changed from smooth to “bumpy” surfaced morphology when the temperature is switch...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752767/ https://www.ncbi.nlm.nih.gov/pubmed/31536610 http://dx.doi.org/10.1371/journal.ppat.1007996 |