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Molecular basis of dengue virus serotype 2 morphological switch from 29°C to 37°C

The ability of DENV2 to display different morphologies (hence different antigenic properties) complicates vaccine and therapeutics development. Previous studies showed most strains of laboratory adapted DENV2 particles changed from smooth to “bumpy” surfaced morphology when the temperature is switch...

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Detalles Bibliográficos
Autores principales: Lim, Xin-Ni, Shan, Chao, Marzinek, Jan K., Dong, Hongping, Ng, Thiam Seng, Ooi, Justin S. G., Fibriansah, Guntur, Wang, Jiaqi, Verma, Chandra S., Bond, Peter J., Shi, Pei-Yong, Lok, Shee-mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752767/
https://www.ncbi.nlm.nih.gov/pubmed/31536610
http://dx.doi.org/10.1371/journal.ppat.1007996