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Osmolytes ameliorate the effects of stress in the absence of the heat shock protein Hsp104 in Saccharomyces cerevisiae

Aggregation of the prion protein has strong implications in the human prion disease. Sup35p is a yeast prion, and has been used as a model protein to study the disease mechanism. We have studied the pattern of Sup35p aggregation inside live yeast cells under stress, by using confocal microscopy, flu...

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Detalles Bibliográficos
Autores principales: Bandyopadhyay, Arnab, Bose, Indrani, Chattopadhyay, Krishnananda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752772/
https://www.ncbi.nlm.nih.gov/pubmed/31536559
http://dx.doi.org/10.1371/journal.pone.0222723